Product Name: Azone

Synonyms: Azon; Laurocapram; 1-Dodecylazacycloheptan-2-one; N-Dodecylcaprolactam; 1-Dodecylhexahydro-2H-azepin-2-one

Molecular Formula: C18H35NO

Molecular Weight: 281.48

CAS No.: 59227-89-3

EINECS: 261-668-9

Description

Azone is a percutaneous enhancer. Upon application to the skin, laurocapram interacts with lipids in the stratum corneum and may enhance the ability of the skin to absorb a hydrophilic chemical.

Benefits

1. it can form emulsion with water, dissolve in various organic solvents, have good lubricity, promote hydrophilic lipophilic drug activity or cosmetics nutrients penetrate into the skin, greatly shorten the retention time of drugs in the stratum corneum, significantly improve the efficacy and beauty effect of drugs.

2. Laurylamine has obvious transdermal auxiliary effect on hydrophilic and lipophilic drugs. It has a good auxiliary effect on a variety of emulsified or colloidal plant extracts, especially alkaloids.

3. It can be considered as a complex of decyl methyl sulfoxide and pyrrolidone, which has good new penetration enhancer and skin irritation. It can promote the transdermal absorption of drugs through the skin barrier, such as corticosteroids, indomethacin, fluorouracil, hydroquinone and other drugs, improve the local and systemic blood drug concentration, and improve the bioavailability of drugs.