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Product Name: Genistein

Synonyms: 4',5,7-Trihydroxyisoflavone

Molecular Formula: C15H10O5

Molecular Weight: 270.24

CAS No.: 446-72-0
EINECS: 207-174-9

 

Description:

Genistein is a soy-derived isoflavone and phytoestrogen with antineoplastic activity. Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities.

Product details

Product Name: Genistein

Synonyms: 4',5,7-Trihydroxyisoflavone

Molecular Formula: C15H10O5

Molecular Weight: 270.24

CAS No.: 446-72-0
EINECS: 207-174-9

 

Description:

Genistein is a soy-derived isoflavone and phytoestrogen with antineoplastic activity. Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities.

 

The chemical compound Genistein works through two primary ways. The first one involves decreasing the activities of estrogen in the body, and the second one includes lowering the effects of estrogen.

 

The chemical compound exerts these effects by binding to the estrogen receptors found inside the body. Once it is linked to the estrogen receptors, genistein stimulates those receptors.

 

Function:

1.      Prevention of cancer

2.      Management of osteoporosis

3.      Management of heart diseases

4.      Prevention of menopausal symptoms

5.      Protects the intestine from radiation