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Paeonol
Product details

Paeonol  

 

Paeonol [552-41-0]

Name

Paeonol

Synonyms

2'-Hydroxy-4'-methoxyacetophenone; 1-(2-hydroxy-4-methoxyphenyl)ethan-1-one

Molecular Formula

C9H10O3

Molecular Weight

166.18

CAS Registry Number

552-41-0

EINECS

209-012-2

Melting point

49-52 ºC

Flash point

>110 ºC

 

Description:

Paeonol has anticancer, anti-inflammatory, antioxidant and cardiovascular protective activities, it shows a novel inhibitory role on neuroinflammation, and presents a new candidate agent for the development of therapies for inflammation-related neurodegenerative diseases. Paeonol suppresses lipopolysaccharide-induced inflammatory cytokines.

 

Pharmacological effects:

Paeonol has analgesic, anti-inflammatory, antipyretic and anti-allergic effects. It has obvious analgesic effect on pain caused by physical or chemical factors such as tail and acetic acid. It has obvious inhibitory effects on inflammatory reactions caused by carrageenan, egg white, formaldehyde, histamine, serotonin, bradykinin, xylene and endotoxin. It has obvious antipyretic effect on the increase of body temperature caused by typhoid vaccine and triple vaccine. It has an inhibitory effect on allergic reactions of type II, III and IV.

It has the functions of sedative, hypnotic, antibacterial, anti-inflammatory, anti-oxidation and blood pressure lowering. In dailyization, paeonol can inhibit the production of O2-free radicals in cells, which can whiten the skin and restore the pigmentation in the skin. It eliminates siltation and plaque; it also has anti-inflammatory, anti-inflammatory, anti-allergic, anti-viral and other effects. It has good therapeutic and health effects on pigmentation, muscle pain, itchy skin, psoriasis, banded sores and eczema. In addition, it has a good effect in toothpaste, gargle, tooth powder and toothache.

(1) It is added to the cosmetic cream to promote blood circulation of the facial skin, activate the aging epidermal cells, eliminate wrinkles, remove spots, and moisturize the skin.

(2) added to the shampoo, can dandruff, itching, conditioning hair, moisturizing, soft, bright, and promote hair growth.

(3) added to the mask liquid, can make the skin white and tender, anti-aging, especially good for acne.

(4) It is added to the fragrance bath and soap to promote skin metabolism, improve skin tone and remove acne.

(5) It can be added to toothpaste and gargle to relieve swelling and pain, prevent dental caries, cover bad breath and clean the mouth.