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D-glutamic Acid
Product details

D(-)-Glutamic acid [6893-26-1]

Name

D(-)-Glutamic acid

Synonyms

D-2-Aminoglutaric acid; (R)-2-Aminopentanedioic acid

Molecular Formula

C5H9NO4

Molecular Weight

147.13

CAS Registry Number

6893-26-1

EINECS

230-000-8

Melting point

200-202 ºC

alpha

-31.3 º (c=10, 2 N HCl)

Water solubility

7 g/L (20 ºC)

 

 

General Description:

D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.

 

Application:

D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors.